Preventive effect of estrogen on depression-like behavior induced by chronic restraint stress
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منابع مشابه
Chronic Administration of Baicalein Decreases Depression-Like Behavior Induced by Repeated Restraint Stress in Rats
Baicalein (BA), a plant-derived active flavonoid present in the root of Scutellaria baicalensis, has been widely used for the treatment of stress-related neuropsychiatric disorders including depression. Previous studies have demonstrated that repeated restraint stress disrupts the activity of the hypothalamic-pituitary-adrenal (HPA) axis, resulting in depression. The behavioral and neurochemica...
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Background and Objective: Many studies demonstrate that cognitive empowerment reduces the risk of depression. Anti-depressant properties of Nepeta menthoides has also been reported. This study aimed to determine the effects of mental exercise and Nepeta menthoides and also to compare both of them on reserpine-induced depression in rats. Materials and Methods: Male rats were divided into 8 grou...
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Depression is a heterogenous, multifaceted disorder with symptoms manifested at the psychological, behavioral and physiological level. Therefore, present study was designed as a model to analyze the long lasting effects of methylmercury chloride in male rats with a focus on depression like behavior. Male albino rats of Wistar strain were exposed orally to a dose of 2 mg/kg of methylmercury chlo...
متن کاملIncoordination among Subcellular Compartments Is Associated with Depression-Like Behavior Induced by Chronic Mild Stress
BACKGROUND Major depressive disorder is characterized as persistent low mood. A chronically stressful life in genetically susceptible individuals is presumably the major etiology that leads to dysfunctions of monoamine and hypothalamus-pituitary-adrenal axis. These pathogenic factors cause neuron atrophy in the limbic system for major depressive disorder. Cell-specific pathophysiology is unclea...
متن کاملEffect of Voluntary Exercise Training on Corticosterone Level and Immobility Behavior Induced by Chronic Stress in Rats
Background: Depression is a common mood disorder that in the long-term impairs thoughts, behavior, feelings, and health. Chronic unpredictable stress is one of the factors that can cause depression. Objectives: To investigate the effect of voluntary exercise training on immobility behavior (caused by chronic unpredictable stress) and serum corticosterone concentration. Materials & Methods: A ...
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ژورنال
عنوان ژورنال: Neuroscience Bulletin
سال: 2010
ISSN: 1673-7067,1995-8218
DOI: 10.1007/s12264-010-0609-9